Category: Science and Technology

This Book Summary

Lifespan: Why We Age, and Why We Don’t Have To is a non-fiction book authored by Australian biologist David Andrew Sinclair and journalist Matthew LaPlante and published by Atria Books on September 10, 2019. In Lifespan, the authors examine how technology, diet, exercise and lifestyle changes including intermittent fasting and cold exposure have the potential to enhance human longevity.

A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?

In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”

This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.

Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, this audio book will forever change the way we think about why we age and what we can do about it.

Book by David A. Sinclair, Matthew D. Laplante Reviews

As one of the pioneers in longevity research, David challenged status quo and demonstrated that nature’s longevity genes seemed to be conserved throughout biology. This is good news, because the changes that occur with aging seem to be correctable later in life. This isn’t another self-help book with meal plans and shopping lists. Instead, it will guide you through the real challenges and progress on our path to not just living longer, but importantly, living healthier.

Although this is plenty technical, it’s not an academic tome. Anyone, researcher or layman alike, will be able to follow the story thanks to the inclusion of so many personal accounts and reflections. After finishing, you will have a new perspective and hopefully realize that we have the ability right now to extend healthspan and the very real possibility of extending lifespan in the coming decade.

We met in 2009 and he encouraged me to write collaborative journal articles (metabolic winter hypothesis and oxidative priority) and now that work ultimately is the basis for our book, The Healthspan Solution, which focuses more on what we can achieve with diet. It’s been an honor working with him and having a man of his insight as a mentor and friend. (R. Cronise)

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Listen or Download Lifespan: Why We Age—and Why We Don’t Have To Audiobook. Streaming and download audiobook to your computer, tablet, iPhone and android. You Can Also Listen Similar Best Science and Technology Audiobook And More Genre Like Romance, thrillers, young adult, Fiction, business and bios. Browse around, check out our recommendations and take a look at what other people are listening to. Lifespan Audiobook Free debuted at #11 on The New York Times hardcover nonfiction bestseller list on September 28, 2019.

The book received mixed reviews from critics. “If you’re even mildly hopeful about dunking a basketball at the age of 50, or hiking the Appalachian Trail at 70, or blowing 100 candles out on your birthday cake someday, you might consider making room for Lifespan on your bookshelf,” one reviewer wrote for Outside.

A review for Boston Magazine called Sinclair “one of science’s most controversial figures” and said many in the scientific community were skeptical of claims he made about human longevity. University of Alabama biology professor Steven N. Austad said, “David is a good friend, but I do think he’s been guilty of making excessive claims.”

In a 2019 interview, Sinclair dismissed the idea that longer lifespans could lead to overpopulation. “Population growth will level off within the next couple of decades, and healthier people are having fewer children,” Sinclair said. “The global population is already stabilizing, and in many advanced countries going down, so people’s fear that the world will be overpopulated with frail old people is completely wrong.”

This Book has three parts. “Part I: What We Know (The Past)” contains three chapters. “Part II: What We’re Learning (The Present)” contains four chapters. “Part III: Where We’re Going (The Future)” contains two chapters. The book also contains an introduction and conclusion. The authors begin by seeking to characterize how professionals view the hallmarks of aging, including genomic instability caused by DNA damage; alterations to the epigenome that controls which genes are turned on and off; loss of healthy protein maintenance, known as proteostasis; exhaustion of stem cells; and the production of inflammatory molecules. “Address one of these, and you can slow down aging,” the authors argue. “Address all of them, and you might not age.”